Key Takeaways
- Singapore is Southeast Asia's longevity hub — more advanced clinics, better regulation, and physicians experienced with cutting-edge protocols.
- Chi Longevity (Four Seasons) is the flagship — comprehensive assessments starting at SGD 3,000–5,000.
- NUS Centre for Healthy Longevity offers research-backed programs and clinical trials.
- For Malaysians, a quarterly trip across the Causeway (or short flight) for specialist longevity consultations can be highly worthwhile.
- Expect to spend SGD 2,000–10,000+ per visit depending on services (RM 7,000–35,000+).
Note: We have no commercial relationships with any clinics mentioned. This review is based on publicly available information, patient reports, and our research.
Why Singapore for Longevity?
Singapore punches far above its weight in longevity medicine. Several factors make it SEA's leading destination:
- Physician quality: Singapore attracts top medical talent from around the world. Many longevity physicians have trained in the US, UK, or Australia and stay current with the latest research.
- Regulatory environment: Singapore's HSA (Health Sciences Authority) provides clearer regulatory frameworks than most SEA countries, creating a more trustworthy clinical environment.
- Research infrastructure: NUS, NTU, Duke-NUS, and A*STAR conduct cutting-edge aging research. This research feeds directly into clinical practice.
- Wealth concentration: Singapore's high-net-worth population sustains premium longevity services that wouldn't be viable in smaller markets.
- Proximity to Malaysia: 1 hour from JB, 1-hour flight from KL. Same timezone. Easy for Malaysians to access.
The Top Longevity Clinics
1. Chi Longevity
Location: Four Seasons Hotel, Orchard Road
The most prominent dedicated longevity clinic in Southeast Asia. Chi Longevity positions itself as a comprehensive "longevity optimisation centre" rather than a traditional medical clinic.
Services
- Longevity Assessment: Comprehensive health evaluation including advanced blood panels, body composition analysis, cardiovascular fitness testing, cognitive assessment, and biological age testing
- Genomic Analysis: Whole genome sequencing or targeted panels with clinical interpretation
- Advanced Imaging: Full-body MRI screening, coronary calcium scoring, DEXA body composition
- IV Therapy: NAD+, glutathione, high-dose vitamin C, Myers cocktail
- Hormone Optimisation: Bioidentical hormone replacement, thyroid optimisation
- Pharmacological Protocols: Rapamycin, metformin, and other longevity medications prescribed by physicians experienced with off-label use
- Senolytic Protocols: Dasatinib + quercetin courses under medical supervision
- Personalised Supplement Programs: Evidence-based supplementation with ongoing monitoring
Pricing (Estimated, SGD)
| Service | Price (SGD) | Approx. RM |
|---|---|---|
| Initial Longevity Assessment | 3,000–5,000 | 10,000–17,500 |
| Comprehensive Assessment + Imaging | 5,000–10,000 | 17,500–35,000 |
| Follow-up Consultation | 300–500 | 1,050–1,750 |
| NAD+ IV Drip | 500–1,200 | 1,750–4,200 |
| Annual Membership / Concierge | 10,000–25,000 | 35,000–87,500 |
Who it's best for: High-net-worth individuals seeking a comprehensive, physician-led longevity program. If budget is less of a concern and you want everything under one roof with world-class physicians, Chi Longevity is the benchmark in SEA.
2. NUS Centre for Healthy Longevity (CHL)
Location: National University Health System (NUHS), Kent Ridge
A research-led longevity centre affiliated with the National University of Singapore. Less luxury than Chi Longevity, but deeply rooted in evidence-based medicine and active clinical research.
Services
- Healthy Longevity Clinic: Clinical assessments focused on aging biomarkers and functional decline prevention
- Clinical Trials: Access to cutting-edge longevity interventions being studied (rapamycin, senolytics, exercise interventions)
- Research Programs: The Singapore Longitudinal Ageing Study and other population-level aging research
- Multi-disciplinary Team: Geriatricians, cardiologists, neurologists, exercise physiologists
Pricing
As a university-affiliated centre, pricing is generally lower than private longevity clinics. However, services are more research-oriented and may involve clinical trial participation.
- Clinical consultations: SGD 150–400
- Assessment programs: SGD 500–2,000
- Clinical trials: Often free or subsidized for participants
Who it's best for: Science-minded individuals who want evidence-based approaches and are potentially willing to participate in clinical research. Less "luxury," more rigour.
3. Functional Medicine & Anti-Aging Clinics
Several established clinics in Singapore offer longevity-adjacent services:
Notable Mentions
- Dr. Mark Hyman's UltraWellness Center (Singapore partner) — functional medicine approach with longevity focus
- Mente Health — brain health and cognitive longevity focus
- Raffles Medical Executive Health Screening — comprehensive executive health screening with some advanced biomarkers
- Mount Elizabeth / Gleneagles Singapore — standard executive health screenings; not longevity-specific but can run comprehensive blood panels
- Various GP practices with longevity interest — a growing number of Singapore GPs are incorporating longevity medicine into their practice
What to Expect From a Longevity Clinic Visit
Initial Assessment (First Visit)
A comprehensive first visit at a top longevity clinic typically includes:
- Detailed medical history — including family history, lifestyle factors, sleep, exercise, stress, diet
- Advanced blood panel — going far beyond standard screening (see our blood test guide for the full panel)
- Body composition analysis — DEXA scan (bone density + body fat + muscle mass) or InBody
- Cardiovascular assessment — ECG, possibly VO2max testing, coronary calcium score
- Cognitive assessment — baseline cognitive function testing
- Physical function testing — grip strength, balance, gait speed, flexibility
- Biological age testing — epigenetic clocks (TruAge, GrimAge)
- Personalised report — detailed analysis of results with actionable recommendations
Follow-Up Protocol
After the initial assessment, a typical longevity clinic relationship involves:
- Quarterly blood work monitoring (can often be done at local labs in KL and results sent to the Singapore physician)
- Quarterly or biannual physician consultations (in-person or telemedicine)
- Ongoing supplementation and medication management
- Annual comprehensive reassessment
Is It Worth the Trip From Malaysia?
The Case FOR Going to Singapore
- Physician experience: Singapore longevity doctors have more experience with rapamycin prescribing, senolytic protocols, and hormone optimization than most Malaysian practitioners
- Regulatory trust: HSA oversight means you can be more confident in treatment quality
- Comprehensive services: One-stop access to advanced imaging, blood work, and physician consultation
- Off-label prescriptions: Singapore physicians are more willing to prescribe rapamycin and other longevity medications off-label
- Telemedicine follow-ups: After the initial visit, many clinics offer virtual consultations, reducing the need for frequent travel
The Case AGAINST
- Cost: Singapore pricing is 2–5× higher than equivalent services in KL. A SGD 5,000 assessment could be replicated for RM 5,000–8,000 in KL if you know the right labs and doctors.
- Travel overhead: Even for Malaysians, a Singapore day trip involves 2–4 hours of travel each way, plus immigration queues at JB–Woodlands
- Blood work is blood work: The actual laboratory tests are the same whether done at Pathlab KL or a Singapore lab. You're paying a premium for interpretation, not the tests themselves.
- Growing KL options: Malaysia's functional medicine and longevity scene is growing. More KL doctors are becoming longevity-literate each year.
The Peak Protocol Verdict
Recommended approach:
- Initial comprehensive assessment at a Singapore longevity clinic (Chi Longevity or NUS CHL). This establishes baseline, gets you access to an experienced physician, and creates a personalised protocol.
- Quarterly blood work done locally in KL (Pathlab/BP Lab — much cheaper)
- Telemedicine follow-ups with your Singapore physician (most offer this)
- Annual reassessment in Singapore — one trip per year for the comprehensive workup
Total annual cost: SGD 4,000–8,000 (RM 14,000–28,000) including one in-person assessment + quarterly remote follow-ups + local blood work. Expensive, but a fraction of what chronic disease treatment costs in later life.
Comparison: Singapore vs KL Longevity Options
| Factor | Singapore | KL |
|---|---|---|
| Physician longevity expertise | ⭐⭐⭐⭐⭐ | ⭐⭐⭐ |
| Advanced testing availability | ⭐⭐⭐⭐⭐ | ⭐⭐⭐⭐ |
| Off-label prescribing (rapamycin etc) | ⭐⭐⭐⭐ | ⭐⭐ |
| Cost | 💰💰💰💰💰 | 💰💰💰 |
| Convenience | ⭐⭐ (travel required) | ⭐⭐⭐⭐⭐ |
| IV therapy options | ⭐⭐⭐⭐⭐ | ⭐⭐⭐⭐ |
| Regulatory oversight | ⭐⭐⭐⭐⭐ | ⭐⭐⭐ |
| Stem cell therapy | ⭐⭐⭐⭐ | ⭐⭐⭐ (more caveat emptor) |
Practical Tips for Malaysians Visiting Singapore Clinics
- Book early: Top longevity physicians have wait times of 2–6 weeks
- Bring existing blood work: If you've done recent tests at Pathlab/BP Lab, bring the results — saves money and gives the physician baseline data
- Fly, don't drive: For KL residents, a 1-hour flight to Changi is less exhausting than the JB drive. Budget airlines offer RM 100–200 fares.
- Combine trips: Schedule your longevity clinic visit alongside other Singapore errands to maximize the trip
- Ask about telemedicine: Most clinics offer virtual follow-ups. Confirm this upfront so you don't need to travel for every consultation.
- Currency advantage: At ~3.5 RM per SGD, Singapore is expensive. Budget accordingly.
- Insurance: Most Malaysian medical insurance does not cover longevity/wellness assessments in Singapore. Expect to pay out-of-pocket.
The Future: Singapore's Longevity Ecosystem
Singapore is investing heavily in longevity science and infrastructure:
- National longevity research funding — the Singapore government has allocated significant research budgets to aging through A*STAR and NRF
- SG100 initiative — various government and private programs targeting health span extension
- Biotech cluster — Biopolis and Tuas Biomedical Park house aging-focused biotech companies
- Growing clinic ecosystem — expect 3–5 more dedicated longevity clinics to open by 2028 as demand grows
For Malaysian longevity enthusiasts, Singapore's proximity and advancing capabilities make it a natural "longevity healthcare" extension — especially for services not yet available in KL.
Bottom Line
Singapore is Southeast Asia's clear leader in longevity medicine. For Malaysians serious about proactive health optimization, establishing a relationship with a Singapore longevity clinic is a worthwhile investment — particularly for initial assessment, rapamycin prescriptions, and access to cutting-edge protocols.
But don't let Singapore's premium options prevent you from starting. Comprehensive blood work in KL costs a fraction of Singapore prices and gives you 80% of the actionable data. An evidence-based supplement stack from Shopee doesn't require a Singapore consultation. And the most powerful longevity interventions — fasting, exercise, sleep — are free regardless of where you live.
Start where you are. Upgrade when ready.
This article is for informational purposes only. Clinic details and pricing may change. Verify current offerings directly with the clinics mentioned.